![]() At the same time, we traced the relevant references of the included literature as a supplement to further search the possibly relevant literature. We used following search terms: (“high flow nasal cannula” OR “HFNC” OR “high flow nasal oxygen” OR “high flow oxygen therapy” OR “high flow nasal cannula oxygen therapy”) AND (“Pulmonary Disease” OR “Chronic Obstructive” OR “Chronic Obstructive Pulmonary Disease” OR “Chronic Obstructive Lung Disease” OR “COPD” OR “Chronic Obstructive Airway Disease” OR “COAD” OR “chronic airflow obstructions” OR “pulmonary emphysema”). The search time limit is from the establishment of the database to Dec 31, 2020. We searched the Cochrane Clinical Trials Database, EMBASE, CINAHL, PubMed, web of science, Wanfang, and Weipu Knowledge Network for randomized controlled trials(RCTs). We conducted and reported this meta-analysis and systematic review in compliance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Therefore, we aimed to conduct a meta-analysis of the application of HFNC in the treatment of patients with COPD and type II respiratory failure, to evaluate the efficacy and safety of HFNC, thereby providing a basis for the clinical treatment of COPD and respiratory failure. The effects and safety of HFNC treatment in patients with COPD and type II respiratory failure remain unclear. However, several studies have shown that HFNC can be used in patients with AECOPD and type II respiratory failure, but it has no effect on the incidence of patients’ tracheal intubation, length of hospital stay, and incidence of adverse events. Some studies have also shown that HFNC can improve oxygenation in patients with COPD. Studies have shown that the use of HFNC oxygen therapy for COPD patients can reduce the frequency of exacerbations and improve exercise capacity and quality of life. HFNC can improve ventilation and oxygenation and improve comfort by providing oxygen that is heated and humidified with precise oxygen concentration. It can reduce PaCO 2 by using the flushing effect of high flow and adjust the oxygen flow and oxygen concentration separately to avoid the high concentration of oxygen causing respiratory depression in patients. High-flow nasal cannula (HFNC) is a new type of non-invasive respiratory assistance method. The poor comfort and mask intolerance can easily lead to tracheal intubation and cause NIV treatment failure. However, the design of NIV masks and nasal masks has disadvantages such as facial compression, affecting patient communication, eating and sleep. Traditional oxygen therapy uses low-flow oxygen, but some patients' hypoxia or hypercapnia are difficult to correct, and noninvasive ventilation (NIV) has gradually become the gold standard for the treatment of patients with AECOPD and type II respiratory failure. Oxygen therapy is the main treatment method for patients with COPD and hypoxemia. Acute exacerbation of COPD and complications are the main causes of death. There are nearly 100 million COPD patients in China, and the prevalence of COPD in people over 40 years old is 13.7%. ![]() Future studies with larger sample size and strict design are needed to further elucidate the role of HFNC in COPD and respiratory failure.Ĭhronic obstructive pulmonary disease (COPD) is a common chronic disease characterized by persistent airflow limitation. HFNC is more advantageous over NIV in the treatment of COPD and type II respiratory failure. ResultsĪ total of 6 RCTs involving 525 COPD and type II respiratory failure patients. We used Revman5.3 software for statistical analysis of collected data. Two researchers independently screened the literature according to the inclusion and exclusion criteria, and evaluated the quality of the literature and extracted data. databases up to for randomized controlled trials (RCTs) on the use of HFNC therapy in patients with COPD and type II respiratory failure. We aimed to evaluate the efficacy and safety of HFNC therapy in patients with COPD and type II respiratory failure, to provide evidence to the clinical COPD management. High-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) have been used for the treatment of COPD and respiratory failure in clinical settings. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |